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Archive for the ‘RNAi’ Category

siRNA for inhibiting HIV-I replication

Posted in Gene Expression, HIV, Medicine, RNAi on November 11, 2007 | 2 Comments »

RNAi is fast emerging as a wonderful tool for inhibiting gene expression in a sequence specific manner. The applications of this technology are two-fold: to study gene function, and use as a therapeutic agent in treating many diseases. As a therapeutic agent it finds applications in antiviral treatments because RNAi has been shown to successfully [...]

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RNAi for pest control: Will it replace the Bt gene?

Posted in Biotechnology, RNAi on November 5, 2007 | Leave a Comment »

Transgenic plants expressing Bt gene have been widely used for pest control for the past several years. However, due to certain limitations associated with using this technology scientists have been looking for alternatives, and they found one in RNAi. The researchers at the Chinese Academy of Sciences, Shanghai, and at Monsanto and Devgen, a Belgian [...]

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piRNAs

Posted in Gene Expression, RNA silencing, RNAi on October 25, 2007 | Leave a Comment »

Piwi-interacting RNAs (piRNA) are a class small of RNA molecules that are expressed uniquely in mammalian spermatogenic cell lines. These are 26–31 nucleotides long and bigger that miRNAs and siRNAs. They are so named because of their capability of forming RNA-protein complexes with Piwi proteins. Piwi proteins are part of the family of Argonaute [...]

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