This post is a tribute to Arthur Kornberg. He died of respiratory failure on Friday in Stanford, California at the age of 89. He discovered the enzyme DNA polymerase, which replicates the DNA molecule. The search for an enzyme that could synthesize DNA started in 1955, which finally culminated in 1959 with a Nobel Prize to Arthur Kornberg in medicine. He and his co-workers purified and characterized DNA polymerase from E. coli. The enzyme they purified is named DNA polymerase I. Four other DNA ploymerases are found in E. coli. The enzyme has also been named Kornberg Enzyme in honour of the scientist. The enzyme is made of a single polypeptide and has a mol wt of 103,000. Read the full story here.
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